Anti-GLI2 antibody (AAS85318E)

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  • (Catalog#: AAS85318E)
100ul
$125.00
Discontinued

Target and Product Information

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Description of Target:
GLI2 encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
Gene Symbol:
GLI2
Official Gene Full Name:
GLI family zinc finger 2
Alias Symbols:
HPE9; THP1; THP2
Protein Accession# :
NP_084655
Nucleotide Accession#:
NM_030379
Swissprot Id:
P10070
Host:
Rabbit
Clonality:
Polyclonal
Protein Size (# AA):
1258
Molecular Weight:
133kDa
Application:
WB, IHC
Immunogen:
Synthetic peptide corresponding to amino acids 283-343 of Human GLI2 protein, P10070
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml.
Predicted Homology:
Human
Species Reactivity:
Human
Datasheets / Downloads:
AAS85318E
Peptide Sequence:
KENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSP
Blocking Peptide:
Peptide #: EAS85318
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Protocols & Procedures

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Protocol:
Tips Information: