Anti-PAX2 antibody (AAS59008C)

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  • (Catalog#: AAS59008C)
100ul
$125.00
Discontinued
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Target and Product Information

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Description of Target:
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
Gene Symbol:
PAX2
Official Gene Full Name:
Paired box 2
Alias Symbols:
RP11-179B2.1
Protein Accession# :
NP_000269
Nucleotide Accession#:
NM_000278
Swissprot Id:
Q02962
Host:
Rabbit
Clonality:
Polyclonal
Protein Size (# AA):
417
Molecular Weight:
45kDa
Application:
WB
Partner Proteins:
ID2, MAPK8, MAPK8IP1, PAXIP1, RB1, SFRP2, WT1, MAPK8, MAPK8IP1, PAXIP1
Immunogen:
Synthetic peptide corresponding to amino acids 161-221 of Human PAX2 protein, Q02962
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml.
Predicted Homology:
Bovine; Chicken; Dog; Guinea pig; Human; Pig; Rabbit; Sheep; Zebrafish; African clawed frog; Mouse; Rat
Datasheets / Downloads:
AAS59008C
Peptide Sequence:
PGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSG
Blocking Peptide:
Peptide #: EAS20312
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Antibody Reviews and Data(1)

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Product Protocols: PAX2 Antibody tested by IHC with human kidney (AAS59008C)

Antibody Verify is the original manufacturer of this PAX2 antibody.
Click here to view the PAX2 antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: PAX2 antibody (AAS59008C)
IHC Information:
Rabbit Anti-PAX2 Antibody
Catalog Number: p100859
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
IHC Image:

Protocols & Procedures

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Protocol:
Tips Information: